Author

Jong Bin Choi

Stanford MedicineORCID 0000-0002-7017-1775Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:human· 4 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Anca M. PașcaiD· 4 shared Dhriti NagariD· 3 shared Li LiiD· 3 shared Saw HtuniD· 3 shared Alyssa PunoiD· 2 shared Seyeon ParkiD· 2 shared Amanda EverittiD· 1 shared Anna J. VossiD· 1 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersNeuroscience

Anca M. PașcaORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Adrenomedullin Restores Mitochondrial Bioenergetics and Rescues Interneuron Phenotypes in Human Models of 22q11.2 Deletion Syndrome

Dhriti Nagar, Jong Bin Choi, Zunsong Hu, Li Li, Madison S. House, Seyeon Park, Bailey Abel, Anushka Nikhil, Meghali Aich, Saw Htun, Katja Gabriele Weinacht, Zhaohui Gu, Anca M. Pașca

This study identifies mitochondrial dysfunction in 22q11.2DS interneurons and shows that Adrenomedullin rescues these defects through distinct signaling pathways.

bioRxiv · May 24, 2026 · PreprintNeuroscience

Adrenomedullin restores human cortical interneurons migration defects induced by hypoxia

Alyssa Puno, Wojciech Michno, Li Li, Amanda Everitt, Kate McCluskey, Saw Htun, Dhriti Nagar, Jong Bin Choi, Yuqin Dai, Seyeon Park, Emily Gurwitz, Arthur Jeremy Willsey, Fikri Birey, Anca M. Pașca

The paper shows hypoxia impairs human cortical interneuron migration and demonstrates adrenomedullin can restore this defect through the cAMP/PKA pathway.

eLife · May 15, 2026Peer-reviewedNeuroscience

THE FAM53C/DYRK1A axis regulates the G1/S transition of the cell cycle

Taylar Hammond, Jong Bin Choi, Miles W. Membreño, János Demeter, Roy Ng, Debadrita Bhattacharya, Thuyen N. Nguyen, Griffin G. Hartmann, Caterina I. Colón, Carine Bossard, Jan Marcel Skotheim, Peter K. Jackson, Anca M. Pașca, Seth M. Rubin, Julien Sage

This study identifies FAM53C as a regulator of the G1/S cell cycle transition, showing it interacts with DYRK1A and affects cell cycle progression in cultured cells and organoids.

eLife · Apr 30, 2026Peer-reviewedCell Biology

Hypoxia disrupts circadian rhythms in astrocytes and causes synapse engulfment defects

Li Li, Jong Bin Choi, Chi-Hong Shin, Saw Htun, Sherry Mestan, Anna J. Voss, Jennifer L. Shadrach, Alyssa Puno, Dhriti Nagar, Nephy Ramirez, Daniela Rojo, Samuel H. Lee, Erin M. Gibson, Julia A. Kaltschmidt, Steven A. Sloan, , Anca M. Pașca

This study shows hypoxia disrupts astrocytic circadian rhythms, reducing synaptosome phagocytosis and linking this to ASD-related synapse defects.

bioRxiv · Feb 22, 2024 · PreprintNeuroscience