Author

Ruby Mangalindan

University of Washington

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3

Frequent Co-Authors

Jackson Wezeman· 3 shared Warren LadigesiD· 3 shared Addison Keely· 2 shared Dan Ratner· 2 shared Joo Young ParkiD· 2 shared Manuela Rosenfeld· 2 shared Matthew Tucker· 2 shared Adam B. SalmoniD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersNeuroscience

Jackson Wezeman

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3 papers

Recent·Most cited

Behavioral and neuropathological features of Alzheimer's disease are attenuated in 5xFAD mice treated with intranasal GHK peptide

Matthew Tucker, Gerald Yu Liao, Addison Keely, Joo Young Park, Manuela Rosenfeld, Jackson Wezeman, Ruby Mangalindan, Dan Ratner, Martin Darvas, Warren Ladiges

This study shows intranasal GHK-Cu treatment reduces cognitive impairment, amyloid plaques, and inflammation in 5xFAD mice, suggesting potential as an AD therapy.

Aging Pathobiology and Therapeutics · Sep 23, 2024Peer-reviewedNeuroscience

Intranasal GHK peptide enhances resilience to cognitive decline in aging mice

Matthew Tucker, Addison Keely, Joo Young Park, Manuela Rosenfeld, Jackson Wezeman, Ruby Mangalindan, Dan Ratner, Warren Ladiges

This study shows that intranasal GHK-Cu improves cognitive performance and reduces neuroinflammatory and axonal damage markers in aged mice.

bioRxiv · Nov 16, 2023 · PreprintNeuroscience

Short term treatment with a cocktail of rapamycin, acarbose and phenylbutyrate slows aging in mice

Zhou Jiang, Juan Wang, Denise M. Imai, Timothy A. Snider, Ruby Mangalindan, John Morton, Lida Zhu, Adam B. Salmon, Jackson Wezeman, Jenna J Klug, Jiayi Hu, Vinal Menon, Nicholas A. Marka, Laura Neidernhofer, Warren Ladiges

A cocktail of rapamycin, acarbose, and phenylbutyrate slowed aging in mice by improving health metrics and reducing age-related lesions.

bioRxiv · Oct 21, 2021 · PreprintSystems Biology