CRISPRmap: Sequencing-free optical pooled screens mapping multi-omic phenotypes in cells and tissue
Jiacheng Gu, Abhishek Iyer, Ben Wesley, Angelo Taglialatela, Giuseppe Leuzzi, Sho Hangai, Aubrianna Decker, Ruoyu Gu, Naomi Klickstein, Yuanlong Shuai, Kristina Janković, Lucy Parker-Burns, Yinuo Jin, Jia Yi Zhang, Justin Hong, , Jellert T. Gaublomme
CRISPRmap enables multi-omic optical pooled screens to map gene function in cells and tissue without sequencing, identifying pathogenic mutations and analyzing spatial phenotypes.
bioRxiv · Dec 26, 2023 · PreprintGenomics