Author

Ryan D. Weeks

University of North Carolina at Chapel Hill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:imaging· 1 Organism:zebrafish· 1

Frequent Co-Authors

Adriana S. BeltrániD· 1 shared Antonio PlanchartiD· 1 shared Audra F. BryaniD· 1 shared Austin J. HepperlaiD· 1 shared Baggio EvangelistaiD· 1 shared Giulia FragolaiD· 1 shared Jennifer Ashley EzzelliD· 1 shared Julie NecarsulmeriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Adriana S. BeltránORCID

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1 paper

Recent·Most cited

High-Content Screening Identifies Dithiocarbamates As A Class Of Chemicals That Disrupts TDP-43 Proteostasis

Giulia Fragola, Ryan D. Weeks, Justin Wolter, Audra F. Bryan, Katheryn Natalya Kapfer, Xu Tian, Julie Necarsulmer, Baggio Evangelista, Vanya Bhat, Omeed K Arooji, Adriana S. Beltrán, Tara A. Brennan, Matthew J. Niederhuber, Austin J. Hepperla, Leonard B. Collins, , Todd J Cohen

This study identifies dithiocarbamates as chemicals that disrupt TDP-43 proteostasis by causing aggregation and loss of function through redox imbalance and zinc homeostasis disruption.

bioRxiv · Aug 22, 2026 · PreprintNeuroscience