Author

S. A. Bonnett

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

T. Parish· 3 shared A. B. Rosenbloom· 1 shared A. Bajpai· 1 shared A. Korkegian· 1 shared A. Rininger· 1 shared C. Phan· 1 shared D. Dennison· 1 shared D. Newhouse· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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3 shared papersMicrobiology

T. Parish

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Ultra High-Plex Spatial Proteogenomic Investigation of Giant Cell Glioblastoma Multiforme Immune Infiltrates Reveals Distinct Protein and RNA Expression Profiles

S. A. Bonnett, A. B. Rosenbloom, G. Ong, M. Conner, A. Rininger, D. Newhouse, F. New, C. Phan, S. Ilcisin, H. Sato, J. Lyssand, G. Geiss, J. M. Beechem

This study develops and applies a spatial proteogenomic assay to analyze glioblastoma multiforme samples, revealing distinct RNA and protein expression profiles based on pathology and location.

bioRxiv · Oct 4, 2022Cancer Biology

Identification of 2-amino benzothiazoles with bactericidal activity against Mycobacterium tuberculosis

S. A. Bonnett, J.-A. Jee, S. Chettiar, Y. Ovechkina, A. Korkegian, E. Greve, J. Odingo, T. Parish

The paper identifies 2-amino benzothiazoles with bactericidal activity against Mycobacterium tuberculosis, showing improved potency and reduced cytotoxicity but poor metabolic stability.

bioRxiv · Sep 23, 2022 · PreprintMicrobiology

Phenylhydrazones are active against non-replicating Mycobacterium tuberculosis

S. A. Bonnett, D. Dennison, A. Bajpai, M. Files, T. Parish

This study shows that phenylhydrazones are active against non-replicating Mycobacterium tuberculosis, with some compounds showing enhanced activity under hypoxic conditions.

PLOS ONE · Oct 17, 2018Peer-reviewedMicrobiology

Activation of 2,4-diaminoquinazoline in Mycobacterium tuberculosis by Rv3161c, a putative dioxygenase

E. Melief, S. A. Bonnett, E. S. Zuniga, T. Parish

The paper shows that Rv3161c in M. tuberculosis metabolizes diaminoquinazolines, as evidenced by the presence of the parent compound in a mutant strain and a mono-hydroxylated metabolite in the wild-type.

bioRxiv · Jul 24, 2018Microbiology