Author

S. A. McKenna

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Cherkasov· 1 shared A. L.-F. Mui· 1 shared A. Ming-Lum· 1 shared A. Samiea· 1 shared B. R. Gill· 1 shared C. J. Ong· 1 shared E. Dzananovic· 1 shared E. K. S. McRae· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

A. Cherkasov

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Author profile →

2 papers

Recent·Most cited

Interleukin-10 and Small Molecule SHIP1 Allosteric Regulators Trigger Anti-Inflammatory Effects Through SHIP1/STAT3 Complexes

T. C. Chamberlain, S. T. Cheung, J. S. J. Yoon, A. Ming-Lum, B. R. Gill, S. Shakibakho, E. Dzananovic, F. Ban, A. Samiea, K. Jawanda, J. Priatel, G. Krystal, C. J. Ong, A. Cherkasov, R. J. Andersen, , A. L.-F. Mui

The paper shows IL10 induces a SHIP1/STAT3 complex in macrophages, and SHIP1 activators mimic IL10's anti-inflammatory effects in colitis.

bioRxiv · May 29, 2020Immunology

An RNA guanine quadruplex regulated pathway to TRAIL-sensitization by DDX21

E. K. S. McRae, S. J. Dupas, E. P. Booy, R. S. Piragasam, R. P. Fahlman, S. A. McKenna

This study identifies DDX21's role in regulating MAGED2 protein levels via RNA G-quadruplexes, leading to TRAIL-R2 upregulation and apoptosis sensitivity.

bioRxiv · Mar 26, 2019Biochemistry