Author

S. T. Cheung

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. Bazarna· 1 shared A. Cherkasov· 1 shared A. L.-F. Mui· 1 shared A. Ming-Lum· 1 shared A. Paschen· 1 shared A. Samiea· 1 shared A. W. Chan· 1 shared B. R. Gill· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Bazarna

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Progranulin promotes immune evasion of pancreatic adenocarcinoma through regulation of MHCI expression

P. F. Cheung, J. Yang, K. Krengel, K. Althoff, C. Yip, E. H. Siu, L. W. Ng, K. S. Lang, L. Cham, D. R. Engel, C. Soun, I. Cima, B. Scheffler, J. K. Striefler, M. Sinn, , J. T. Siveke

This study shows that tumor-derived progranulin (PGRN) promotes immune evasion in pancreatic ductal adenocarcinoma by reducing MHC class I expression, and blocking PGRN enhances immune response and slows tumor progression.

bioRxiv · Feb 24, 2021 · PreprintCancer Biology

Interleukin-10 and Small Molecule SHIP1 Allosteric Regulators Trigger Anti-Inflammatory Effects Through SHIP1/STAT3 Complexes

T. C. Chamberlain, S. T. Cheung, J. S. J. Yoon, A. Ming-Lum, B. R. Gill, S. Shakibakho, E. Dzananovic, F. Ban, A. Samiea, K. Jawanda, J. Priatel, G. Krystal, C. J. Ong, A. Cherkasov, R. J. Andersen, , A. L.-F. Mui

The paper shows IL10 induces a SHIP1/STAT3 complex in macrophages, and SHIP1 activators mimic IL10's anti-inflammatory effects in colitis.

bioRxiv · May 29, 2020Immunology