Regulation of Liver Regeneration by hepatocyte O-GlcNAcylation in mice
D. R. Robarts, S. R. McGreal, D. S. Umbaugh, W. S. Parkes, M. Kotulkar, S. Abernathy, N. Lee, H. Jaeschke, S. Gunewardena, S. A. Whelan, J. A. Hanover, N. E. Zachara, C. Slawson, U. Apte
This study shows that O-GlcNAcylation in hepatocytes is essential for proper liver regeneration, with its loss leading to uncontrolled proliferation and tumor formation.
bioRxiv · Oct 14, 2021Pathology