Author

S. Arastu

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

C. Li· 1 shared E. C. Lopes· 1 shared E. White· 1 shared J. D. Rabinowitz· 1 shared J. Lam· 1 shared J. M. Ghergurovich· 1 shared J. Y. Guo· 1 shared M. Sun· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

C. Li

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1 paper

Recent·Most cited

G6PD Maintains Redox Homeostasis and Biosynthesis in LKB1-Deficient KRAS-Driven Lung Cancer

T. Lan, S. Arastu, S. Wang, J. Lam, W. Wang, V. Bhatt, E. C. Lopes, Z. S. Hu, M. Sun, X. Luo, J. M. Ghergurovich, C. Li, X. Su, J. D. Rabinowitz, E. White, J. Y. Guo

This study shows that G6PD is critical for redox balance and biosynthesis in LKB1-deficient KRAS-driven lung cancer, but not in KP tumors, and identifies potential therapeutic strategies.

bioRxiv · Oct 6, 2023 · PreprintCancer Biology