Author

J. M. Ghergurovich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

J. D. Rabinowitz· 2 shared C. Li· 1 shared E. C. Lopes· 1 shared E. White· 1 shared J. Lam· 1 shared J. Y. Guo· 1 shared J. Z. Wang· 1 shared L. Yang· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

J. D. Rabinowitz

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 6, 2023

G6PD Maintains Redox Homeostasis and Biosynthesis in LKB1-Deficient KRAS-Driven Lung Cancer

T. Lan, S. Arastu, S. Wang…·J. Y. Guo

This study shows that G6PD is critical for redox balance and biosynthesis in LKB1-deficient KRAS-driven lung cancer, but not in KP tumors, and identifies potential therapeutic strategies.

DOI 10.1101/2023.10.06.561131

mousemetabolomics

𝕏 PostBluesky

Cancer BiologybioRxivPreprintSep 5, 2020

Methionine synthase supports tumor tetrahydrofolate pools

J. Z. Wang, J. M. Ghergurovich, L. Yang, J. D. Rabinowitz

This study shows methionine synthase (MTR) is crucial for cells to avoid folate trapping and assimilate 5-methyl-THF into other folate species, supporting one-carbon metabolism and tumor growth.

DOI 10.1101/2020.09.05.284521

humanbulk RNA-seq

𝕏 PostBluesky