Genetic, environmental and intrinsic determinants of the human antibody epitope repertoire
S. Andreu-Sanchez, A. R. Bourgonje, T. Vogl, A. Kurilshikov, S. Leviatan, A. J. Ruiz Moreno, S. Hu, T. Sinha, A. Vich Vila, S. Klompus, I. Kalka, K. de Leeuw, S. Arends, I. H. Jonkers, S. Withoff, , A. Zhernakova
This study uses PhIP-Seq to analyze antibody repertoires in 1,443 individuals, showing genetic and environmental factors influence antibody diversity and phenotype associations.
bioRxiv · Dec 7, 2021Immunology