S. Andreu-Sanchez

Mother-Infant Gut Viruses and their Bacterial Hosts: Transmission Patterns and Dynamics during Pregnancy and Early Life

The faecal metabolome and its determinants in inflammatory bowel disease

This study identifies metabolic alterations in IBD patients by analyzing faecal metabolites, metagenomics, host genetics, and clinical data, finding over 300 differentially abundant molecules and associations with microbiota and diet.

HIV-linked gut dysbiosis associates with cytokine production capacity in viral-suppressed people living with HIV

This study links HIV-associated gut dysbiosis to cytokine production capacity in ART-suppressed PLHIV, identifying specific microbial strains associated with immune markers.

Genetic, parental and lifestyle factors influence telomere length

This study identifies factors influencing telomere length across blood cell types, showing genetic, parental, and lifestyle effects, with maternal age's impact mediated by epigenetics.

In-depth characterization of the serum antibody epitope repertoire in inflammatory bowel disease using phage-displayed immunoprecipitation sequencing

This study identifies distinct antibody epitope repertoires in IBD patients using PhIP-seq, revealing differentially abundant antibodies associated with disease subtypes and features.

Genetic, environmental and intrinsic determinants of the human antibody epitope repertoire

This study uses PhIP-Seq to analyze antibody repertoires in 1,443 individuals, showing genetic and environmental factors influence antibody diversity and phenotype associations.

Gut microbial structural variations as determinants of human bile acid metabolism

The paper identifies bacterial structural variants associated with bile acid metabolism in humans using metagenomic data from two Dutch cohorts.

Easymap: a user-friendly software package for rapid mapping by sequencing of point mutations and large insertions

Easymap simplifies mapping-by-sequencing analysis for point mutations and large insertions using NGS data, validated across plant and animal species.

The Dutch Microbiome Project defines factors that shape the healthy gut microbiome

This study identifies environmental and lifestyle factors shaping the gut microbiome in a large Dutch cohort, finding that most microbiome variation is due to environment rather than genetics.