Author

S. Atla

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:virus· 2

Frequent Co-Authors

J. Xiao· 3 shared K. Khatua· 3 shared S. Xu· 3 shared Y. Ma· 3 shared Y. R. Alugubelli· 3 shared C.-C. Cho· 2 shared D. Coleman· 2 shared E. C. Vatansever· 2 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiochemistry

J. Xiao

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Discovery of First-in-Class PROTAC Degraders of SARS-CoV-2 Main Protease

Y. R. Alugubelli, J. Xiao, K. Khatua, S. Kumar, Y. Ma, X. Ma, V. R. Vulupala, S. Atla, L. Blankenship, D. Coleman, B. W. Neuman, W. Liu, S. Xu

This paper develops first-in-class PROTAC degraders of SARS-CoV-2 main protease, showing they reduce MPro levels and exhibit anti-SARS-CoV-2 activity.

bioRxiv · Sep 29, 2023Biochemistry

An Azapeptide Platform in Conjunction with Covalent Warheads to Uncover High-Potency Inhibitors for SARS-CoV-2 Main Protease

K. Khatua, Y. R. Alugubelli, K. Yang, V. Reddy, L. Blankenship, D. Coleman, S. Atla, S. Chaki, Z. Geng, X. Ma, J. Xiao, P.-H. Chen, C.-C. Cho, E. C. Vatansever, Y. Ma, , W. R. Liu

This study develops an azapeptide platform with covalent warheads to identify potent SARS-CoV-2 MPro inhibitors, including MPI89 with a 10 nM EC50 and high selectivity.

bioRxiv · Apr 11, 2023 · PreprintBiochemistry

A Systematic Survey of Reversibly Covalent Dipeptidyl Inhibitors of the SARS-CoV-2 Main Protease

Z. Z. Geng, S. Atla, N. Shaabani, V. R. Vulupara, K. S. Yang, Y. R. Alugubelli, K. Khatua, P.-H. C. Chen, J. Xiao, L. R. Blankenship, X. R. Ma, E. C. Vatansever, C.-C. Cho, Y. Ma, R. Allen, , W. R. Liu

This study systematically evaluates dipeptidyl inhibitors of SARS-CoV-2 main protease, identifying compounds with high antiviral potency and low cytotoxicity.

bioRxiv · Jan 17, 2023Biochemistry