S. B. Lim

Deleterious Mechanical Deformation Selects Mechanoresilient Cancer Cells with Enhanced Proliferation and Chemoresistance

The paper shows that mechanical deformation selects for cancer cells with enhanced proliferation and chemoresistance, linking physical microenvironmental barriers to metastatic malignancy.

Cancer exosomes harbor diverse hypoxia-targeted mRNAs and contribute toward tumor angiogenesis

This study identifies hypoxia-targeted mRNAs in cancer exosomes that promote angiogenesis and reprogram recipient cells.