Author

G. V. Shivashankar

Primary ORCID profile (0000-0002-3445-4567 · 6 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

G. V. ShivashankariD6 papers · Paul Scherrer Institute

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:Hi-C· 1 Assay:imaging· 1

Frequent Co-Authors

A. Mitra· 1 shared B. C. Low· 1 shared C. T. Lim· 1 shared C. Uhler· 1 shared D. S. Jokhun· 1 shared I. Saggio· 1 shared J. Xiao· 1 shared K. Jiang· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperBioengineering

A. Mitra

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3 papers

Recent·Most cited

Adhesome Receptor Clustering is Accompanied by the Colocalization of the Associated Genes in the Cell Nucleus

L. V. Cammarata, C. Uhler, G. V. Shivashankar

The paper shows that genes coding for adhesome receptor proteins are spatially co-localized and co-regulated in the nucleus, with transcription factors also co-localizing to reinforce extracellular matrix sensing.

bioRxiv · Dec 7, 2023 · PreprintCell Biology

Deleterious Mechanical Deformation Selects Mechanoresilient Cancer Cells with Enhanced Proliferation and Chemoresistance

K. Jiang, S. B. Lim, J. Xiao, D. S. Jokhun, M. Shang, X. Song, P. Zhang, L. Liang, B. C. Low, G. V. Shivashankar, C. T. Lim

The paper shows that mechanical deformation selects for cancer cells with enhanced proliferation and chemoresistance, linking physical microenvironmental barriers to metastatic malignancy.

bioRxiv · Jul 22, 2022Cancer Biology

Guiding Irregular Nuclear Morphology on Nanopillar Array for Malignancy Differentiation in Tumor cells

Y. Zeng, Y. Zhuang, A. Mitra, P. Chen, I. Saggio, G. V. Shivashankar, W. Gao, W. Zhao

This paper uses nanopillar arrays to quantify subnuclear morphology in tumor cells, showing it correlates with malignancy and drug response.

bioRxiv · Jan 30, 2022Bioengineering