Author

S. Barrin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

C. Kantari-Mimoun· 2 shared E. Donnadieu· 2 shared A. Eberhardt· 1 shared A. Kaiser· 1 shared A. Kinkhabwala· 1 shared A. Lupo· 1 shared A. Nicolas-Boluda· 1 shared A. Trautmann· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

C. Kantari-Mimoun

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Spatial architecture of CD8+ T cells and DC subsets is critical for the response to immune checkpoint inhibitors in melanoma

E. Gobbini, M. Hubert, A.-C. Doffin, A. Eberhardt, L. Hermet, D. Li, P. Duplouye, S. Barrin, J. Berthet, V. Benboubker, M. Grimont, C. Sakref, J. Perrot, G. Tondeur, O. Harou, , J. Valladeau-Guilemond

This study examines the spatial organization of dendritic cell (DC) subsets and their interactions with CD8+ T cells in melanoma patients, finding that proximity between cDC1 and CD8+ T cells correlates with response to immune checkpoint inhibitors.

bioRxiv · Feb 6, 2024 · PreprintCancer Biology

CAR T cell entry into tumor islets is a two-step process dependent on IFNγ and ICAM-1

C. Kantari-Mimoun, S. Barrin, S. Haghiri, C. Gervais, J. Mittelstaet, N. Mockel-Tenbrinck, A. Kinkhabwala, D. Damotte, A. Lupo, M. Sibony, M. Alifano, L. Vimeux, E. Dondi, N. Bercovici, A. Trautmann, , E. Donnadieu

This study shows CAR T cell entry into tumor islets occurs in two steps, requiring IFNγ and ICAM-1 for effective infiltration.

bioRxiv · May 27, 2020Immunology

Tumor stiffening reversion through collagen crosslinking inhibition improves T cell migration and anti-PD-1 treatment

A. Nicolas-Boluda, J. Vaquero, S. Barrin, C. Kantari-Mimoun, M. Ponzo, G. Renault, P. Deptula, K. Pogoda, R. Bucki, I. Cascone, J. Courty, L. Fouassier, F. Gazeau, E. Donnadieu

This study shows that inhibiting collagen crosslinking reduces tumor stiffness, enhances T cell migration, and improves anti-PD-1 treatment efficacy in mouse tumor models.

bioRxiv · May 19, 2020Cancer Biology