Author

M. Ponzo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:CITE-seq· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

I. Cascone· 2 shared A. Debesset· 1 shared A. Nicolas-Boluda· 1 shared A. Thiolat· 1 shared B. L. Salomon· 1 shared C. F. Magnani· 1 shared C. Houppe· 1 shared C. Kantari-Mimoun· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersImmunology

I. Cascone

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

TNFR2 blockade promotes anti-tumoral immune response in PDAC by targeting activated Treg and reducing T cell exhaustion

A. Debesset, C. Pilon, S. Meunier, O. Bonizec, W. Richer, A. Thiolat, C. Houppe, M. Ponzo, J. Magnan, P. Caudana, J. Tosello boari, S. Baulande, N. H. To, B. L. Salomon, E. Piaggio, , J. L. Cohen

This study shows that blocking TNFR2 reduces Treg activity and T cell exhaustion in PDAC, with improved efficacy when combined with CD40 agonists.

bioRxiv · Jan 22, 2024 · PreprintImmunology

Anti-CD117 CAR T cells incorporating a safety switch eradicate human acute myeloid leukemia and hematopoietic stem cells

C. F. Magnani, R. Myburgh, S. Brunn, M. Chambovey, M. Ponzo, L. Volta, C. Pellegrino, S. Pascolo, C. Miskey, Z. Ivics, J. A. Shizuru, D. Neri, M. G. Manz

This study develops anti-CD117 CAR T cells with a safety switch to target and eliminate acute myeloid leukemia and hematopoietic stem cells in preclinical models.

bioRxiv · Jun 15, 2023Cancer Biology

Tumor stiffening reversion through collagen crosslinking inhibition improves T cell migration and anti-PD-1 treatment

A. Nicolas-Boluda, J. Vaquero, S. Barrin, C. Kantari-Mimoun, M. Ponzo, G. Renault, P. Deptula, K. Pogoda, R. Bucki, I. Cascone, J. Courty, L. Fouassier, F. Gazeau, E. Donnadieu

This study shows that inhibiting collagen crosslinking reduces tumor stiffness, enhances T cell migration, and improves anti-PD-1 treatment efficacy in mouse tumor models.

bioRxiv · May 19, 2020Cancer Biology