Author

D. Damotte

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2

Frequent Co-Authors

E. Donnadieu· 2 shared L. Vimeux· 2 shared M. Alifano· 2 shared A. Di Genova· 1 shared A. Gey· 1 shared A. Gilg Soit Ilg· 1 shared A. Gonzalez-Perez· 1 shared A. Kaiser· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersImmunology

E. Donnadieu

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Differential predictive value of resident memory CD8+T cell subpopulations in non-small-cell lung cancer patients treated by immunotherapy

L. Paolini, T. Tran, S. Corgnac, J.-P. VILLEMIN, M. Wislez, J. Arrondeau, L. Johannes, J. Ulmer, L.-V. Vieillard, J. Pineau, A. Gey, V. Quiniou, P. Barennes, H. P. Pham, n. Gruel, , E. TARTOUR

The paper identifies two TRM subpopulations in NSCLC patients and shows that only DP TRM predicts response to PD-1 blockade immunotherapy.

bioRxiv · Mar 7, 2024Immunology

Mitochondrial metabolism sustains CD8+ T cellmigration for an efficient infiltration into solid tumors

L. Simula, M. Fumagalli, L. Vimeux, I. Rajnpreht, P. Icard, D. An, F. Pendino, D. Damotte, A. Lupo-Mansuet, M. Alifano, M.-C. Alves-Guerra, E. Donnadieu

This study shows mitochondrial metabolism, not glycolysis, is essential for CD8+ T cell migration in 3D tumor environments, and enhancing mitochondrial activity improves CAR T cell infiltration and tumor control.

bioRxiv · Jan 12, 2024Immunology

Disentangling heterogeneity of Malignant Pleural Mesothelioma through deep integrative omics analyses

L. Mangiante, N. Alcala, A. Di Genova, A. Sexton-Oates, A. Gonzalez-Perez, A. Khandekar, E. Bergstrom, J. Kim, C. Giacobi, N. Le-Stang, S. Boyault, C. Cuenin, S. Tabone-Eglinger, F. Damiola, C. Voegele, , Meyer

This study identifies four sources of heterogeneity in MPM using multi-omic factor analysis, showing how genomic events shape molecular profiles and clinical behavior.

bioRxiv · Sep 27, 2021Cancer Biology

CAR T cell entry into tumor islets is a two-step process dependent on IFNγ and ICAM-1

C. Kantari-Mimoun, S. Barrin, S. Haghiri, C. Gervais, J. Mittelstaet, N. Mockel-Tenbrinck, A. Kinkhabwala, D. Damotte, A. Lupo, M. Sibony, M. Alifano, L. Vimeux, E. Dondi, N. Bercovici, A. Trautmann, , E. Donnadieu

This study shows CAR T cell entry into tumor islets occurs in two steps, requiring IFNγ and ICAM-1 for effective infiltration.

bioRxiv · May 27, 2020Immunology