Discovery of nanobodies against SARS-CoV-2 and an uncommon neutralizing mechanism
D. Li, T. Li, B. Zhou, Z. Luo, Y. Lai, S. Huang, Y. Zhou, A. Gautam, S. Bourgeau, S. Wang, J. Bao, J. Tan, D. Lavillette
This study isolates and characterizes two nanobodies against SARS-CoV-2 that neutralize the virus through distinct mechanisms, with one showing efficacy against the Alpha variant and reduced activity against the Beta variant.
bioRxiv · Jul 20, 2021 · PreprintBiochemistry