Author

S. Budhiraja

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Approach:experimental assay· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

C. Park· 3 shared S. Baisiwala· 3 shared A. Sonabend· 2 shared A. U. Ahmed· 2 shared A. Zolp· 2 shared C. Dmello· 2 shared E. Perrault· 2 shared G. Dara· 2 shared

Activity by Year

2021-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

C. Park

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Ribonucleotide Reductase Regulatory Subunit M2 as a Driver of Glioblastoma TMZ-Resistance through Modulation of dNTP Production

E. N. Perrault, J. M. Shireman, E. S. Ali, I. Preddy, P. Lin, C. Park, L. Tomes, A. J. Zolp, S. Budhiraja, S. Baisiwala, C. D. James, I. Ben-Sahra, S. Pott, A. Basu, A. U. Ahmed

This study identifies RRM2 as a driver of TMZ resistance in GBM by modulating dNTP production, showing RRM2 inhibition enhances TMZ efficacy in vivo.

bioRxiv · Nov 23, 2021 · PreprintCancer Biology

CRISPR-Cas9 Screen Reveals PSMB3 Contributes to Gliomagenesis Through Proteasome-Dependent and Independent Mechanisms

S. Baisiwala, S. Budhiraja, A. Zolp, K. Nandoliya, L. Chen, C. Park, E. Perrault, M. Saathoff, C. Dmello, J. Shireman, P. Lin, G. Dara, K. McCortney, C. Horbinski, A. Sonabend, A. U. Ahmed

The paper identifies PSMB3 as a contributor to gliomagenesis through proteasome-dependent and independent mechanisms using a CRISPR-Cas9 screen in GBM.

bioRxiv · Jul 28, 2021 · PreprintCancer Biology

ARF4-mediated Retrograde Trafficking Drives Chemoresistance in Glioblastoma

S. Budhiraja, S. Baisiwala, E. Perrault, S. Cho, K. Nandoliya, G. Dara, A. Zolp, L. Chen, C. Dmello, C. Park, A. Sonabend, A. Ahmed

This study identifies ARF4 as a driver of chemoresistance in glioblastoma through a CRISPR screen and shows it mediates retrograde trafficking of EGFR into the nucleus.

bioRxiv · Jul 18, 2021 · PreprintCancer Biology