Author

S. C. Jang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

B. W. Han· 1 shared C. Lasser· 1 shared E.-J. Kwon· 1 shared G. V. Shelke· 1 shared H. J. Hoffmann· 1 shared H. Lee· 1 shared H.-J. Cha· 1 shared J. Lotvall· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperPharmacology & Toxicology

B. W. Han

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2 papers

Recent·Most cited

Identification of a novel HASPIN inhibitor and its synergism with the PLK1 inhibitor

E.-J. Kwon, K. Mashelkar, J. Seo, Y. Shin, K. Sung, S. C. Jang, S. W. Cheon, H. Lee, B. W. Han, L. S. Jeong, H.-J. Cha

The paper identifies a novel HASPIN inhibitor, LJ4827, and shows its synergistic effect with PLK1 inhibitor BI2536 in lung cancer treatment.

bioRxiv · Sep 1, 2022 · PreprintPharmacology & Toxicology

Regulation of mesenchymal stem cell function by TGFβ-1 on mast cell extracellular vesicles -- role of endosomal retention

Y. Yin, G. V. Shelke, S. C. Jang, C. Lasser, S. Wennmalm, H. J. Hoffmann, J. Nilsson, L. Li, Y. S. Gho, J. Lotvall

The paper shows that mast cell-derived extracellular vesicles carrying TGFβ-1 enhance mesenchymal stem cell migration and MMP activity, with endosomal retention prolonging TGFβ-1 signaling and reducing allergic inflammation.

bioRxiv · Aug 4, 2017Cell Biology