J. Seo

Direct extrusion of multifascicle prevascularized human skeletal muscle for volumetric muscle loss surgery

This paper develops a method to create multifascicle human skeletal muscle scaffolds for volumetric muscle loss repair, showing that cocultured scaffolds regenerate muscle in vivo.

Meta-analysis of the human upper respiratory tract microbiome reveals robust taxonomic associations with health and disease.

This study performs a meta-analysis of URT microbiome data to identify consistent taxonomic associations with health and disease across multiple respiratory conditions.

Darapladib, an inhibitor of Lp-PLA2, sensitizes cancer cells to ferroptosis by remodeling lipid metabolism

This study shows that darapladib, an Lp-PLA2 inhibitor, enhances ferroptosis in cancer cells by altering lipid metabolism and synergizes with GPX4 inhibitors to suppress tumor growth.

IMPASTO: Multiplexed cyclic imaging without signal removal via self-supervised neural unmixing

IMPASTO enables erasureless cyclic imaging for multiplexed spatial proteomics through self-supervised neural unmixing, achieving 30-plex imaging with reduced tissue distortion.

Identification of a novel HASPIN inhibitor and its synergism with the PLK1 inhibitor

The paper identifies a novel HASPIN inhibitor, LJ4827, and shows its synergistic effect with PLK1 inhibitor BI2536 in lung cancer treatment.

Deep Metric Learning Network using Proxies for Chromosome Classification and Retrieval in Karyotyping Test

This paper introduces Proxy-ResNeXt-CBAM, a metric learning network for chromosome classification and retrieval in karyotyping, achieving high accuracy and effective clustering of embeddings.

Gait analysis of healthy rhesus monkeys using a pressure-sensing walkway system

This study analyzed gait parameters of healthy rhesus monkeys using a pressure-sensing walkway, revealing forelimb dominance in weight distribution and symmetric gait patterns.

Novel allelic variant of Lpa1 gene associated with a significant reduction in seed phytic acid content in rice (Oryza sativa L.)

This study identifies a recessive allele in the OsLpa1 gene that significantly reduces phytic acid content in rice seeds by altering enzyme activity.

A proteolytic complex targets multiple cell wall hydrolases in Pseudomonas aeruginosa

This paper identifies CtpA and its partner LbcA as a proteolytic complex in Pseudomonas aeruginosa that degrades peptidoglycan cross-link hydrolases, regulating virulence and cell wall remodeling.