Author

S. de Kivit

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

J. Borst· 3 shared E. Schrama· 2 shared M. Mensink· 2 shared A. J. Morris· 1 shared A. Mazzocca· 1 shared A. Menegakis· 1 shared A. Perrakis· 1 shared C. R. Berkers· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersImmunology

J. Borst

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

TNFR2 costimulation differentially impacts regulatory and conventional CD4+ T-cell metabolism

M. Mensink, E. A. Zaal, T. Tran Ngoc Minh, E. Schrama, C. R. Berkers, J. Borst, S. de Kivit

This study examines how TNFR2 costimulation affects the metabolism of regulatory and conventional CD4+ T-cells, revealing distinct metabolic impacts on each cell type.

bioRxiv · Mar 25, 2022 · PreprintImmunology

Proteomics reveals unique identities of human TGF-β-induced and thymus-derived CD4+ regulatory T cells

M. Mensink, E. Schrama, E. Cuadrado, M. van den Biggelaar, D. Amsen, J. Borst, S. de Kivit

The paper uses proteomics to compare TGF-β-induced iTreg cells with thymus-derived tTreg and Tconv cells, finding iTreg cells have distinct protein expression patterns and lack key Treg signatures.

bioRxiv · Oct 30, 2021Immunology

Autotaxin impedes anti-tumor immunity by suppressing chemotaxis and tumor infiltration of CD8+ T cells

E. Matas-Rico, E. Frijlink, I. van der Haar Avila, A. Menegakis, M. van Zon, A. J. Morris, J. Koster, F. Salgado-Polo, S. de Kivit, T. Lanca, A. Mazzocca, Z. Johnson, J. Haanen, T. N. Schumacher, A. Perrakis, , W. H. Moolenaar

This study shows that ATX secreted by melanoma cells repels CD8+ T cells, reducing their infiltration into tumors and impairing anti-tumor immunity.

bioRxiv · Feb 26, 2020Cancer Biology