Author

M. van den Biggelaar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Assay:proteomics· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Guislain· 2 shared B. P. Nicolet· 2 shared F. P. van Alphen· 2 shared A. A. Mulder· 1 shared A. J. Hoogendijk· 1 shared A. P. Jurgens· 1 shared B. Popovic· 1 shared C. Margadant· 1 shared

Activity by Year

2019-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

A. Guislain

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cell BiologybioRxivDec 10, 2021

Syntaxin 5 determines Weibel-Palade body size and Von Willebrand factor secretion by controlling Golgi architecture

M. Kat, E. Karampini, A. J. Hoogendijk…·R. Bierings

This study identifies Syntaxin 5 as a regulator of Weibel-Palade body size and VWF secretion by controlling Golgi architecture in endothelial cells.

DOI 10.3324/haematol.2021.280121

humanproteomics

𝕏 PostBluesky

ImmunologybioRxivNov 3, 2021

Time-dependent regulation of cytokine production by RNA binding proteins defines T cell effector function

B. Popovic, B. P. Nicolet, A. Guislain…·M. C. Wolkers

The paper identifies RNA binding proteins regulating cytokine production in T cells over time, showing how they influence effector function and anti-tumor responses.

DOI 10.1016/j.celrep.2023.112419

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivOct 30, 2021

Proteomics reveals unique identities of human TGF-β-induced and thymus-derived CD4+ regulatory T cells

M. Mensink, E. Schrama, E. Cuadrado…·S. de Kivit

The paper uses proteomics to compare TGF-β-induced iTreg cells with thymus-derived tTreg and Tconv cells, finding iTreg cells have distinct protein expression patterns and lack key Treg signatures.

DOI 10.1038/s41598-022-23515-z

humanproteomics

𝕏 PostBluesky

ImmunologybioRxivAug 9, 2019

CD29 marks superior cytotoxic human CD8+ T cells

B. P. Nicolet, A. Guislain, F. P. J. van Alphen…·M. Wolkers

This study identifies CD29 as a marker for cytotoxic CD8+ T cells, showing its stability and utility in enhancing anti-tumoral activity.

DOI 10.1073/pnas.1913940117

humanbulk RNA-seq

𝕏 PostBluesky