Dissecting the contributions of tumor heterogeneity on metastasis at single-cell resolution
J. Winkler, W. Tan, C. M. M. Diadhiou, C. S. McGinnis, A. Abbasi, S. Hasnain, S. Durney, E. Atamaniuc, D. Superville, L. Awni, J. V. Lee, J. H. Hinrichs, M. Y. Hein, M. Borja, A. Detweiler, , Z. Werb
This study analyzes single-cell transcriptomes of primary tumors and metastases from breast cancer models, identifying transcriptional differences and gene signatures linked to metastatic potential and patient outcomes.
bioRxiv · Aug 4, 2022 · PreprintCancer Biology