BiochemistrybioRxiv
PERK Kinase Activity is Regulated by Copper Binding-A New Regulatory Paradigm for Modulation of ER Stress Tolerance
S. E. B. Newton, N. R. Beratan, C. Akay-Espinoza…·K. L. Jordan-Sciutto
The paper shows copper binding regulates PERK kinase activity, affecting ER stress tolerance in C. elegans.
DOI 10.1016/j.celrep.2025.116318