Author

S. E. Rossi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

D. Durocher· 3 shared S. Adam· 3 shared A. Alvarez-Quilon· 2 shared H. Melo· 2 shared M. De Marco Zompit· 2 shared M. Stucki· 2 shared N. Hustedt· 2 shared N. Moatti· 2 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersCancer Biology

D. Durocher

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Author profile →

3 papers

Recent·Most cited

The CIP2A-TOPBP1 complex safeguards chromosomal stability during mitosis

M. De Marco Zompit, C. Mooser, S. Adam, S. E. Rossi, A. Jeanrenaud, P.-A. Leimbacher, D. Fink, D. Durocher, M. Stucki

This study identifies CIP2A as a mitosis-specific protein that forms a complex with TOPBP1 to regulate DSB repair and chromosomal stability during mitosis.

bioRxiv · Feb 8, 2021Cell Biology

CIP2A is a prime synthetic-lethal target for BRCA-mutated cancers

S. Adam, S. E. Rossi, N. Moatti, M. De Marco Zompit, T. F. Ng, A. Alvarez-Quilon, J. Desjardins, V. Bhaskaran, G. Martino, D. Setiaputra, S. M. Noordermeer, T. K. Ohsumi, N. Hustedt, R. K. Szilard, N. Chaudhary, , D. Durocher

The paper identifies CIP2A as a synthetic-lethal target in BRCA-mutated cancers by showing its essential role in mitotic chromosome stability and its interaction with TOPBP1.

bioRxiv · Feb 8, 2021 · PreprintCancer Biology

A genetic map of the response to DNA damage in human cells

M. Olivieri, T. Cho, A. Alvarez-Quilon, K. Li, M. J. Schellenberg, M. Zimmermann, N. Hustedt, S. E. Rossi, S. Adam, H. Melo, A. M. Heijink, G. Sastre-Moreno, N. Moatti, R. Szilard, A. McEwan, , D. Durocher

The paper identifies 840 genes involved in the DNA damage response through CRISPR/Cas9 screens and highlights specific gene functions in DNA repair and toxicity mechanisms.

bioRxiv · Nov 18, 2019Cancer Biology