Author

G. Martino

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Evolutionary Biology· 2 Cell Biology· 1 Ecology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. Chiocchio· 3 shared D. Canestrelli· 3 shared R. Bisconti· 3 shared A. Alvarez-Quilon· 2 shared A. Veloso· 2 shared D. Durocher· 2 shared H. Melo· 2 shared J. Desjardins· 2 shared

Activity by Year

2018-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersEvolutionary Biology

A. Chiocchio

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Dual role of brain endothelial Gpr126 in blood-brain barrier development and ischemic stroke

N. Kakogiannos, A. A. Scalise, E. Martini, C. Maderna, S. Magni, G. S. Gullotta, M. G. Lampugnani, F. Iannelli, G. Beznusenko, A. Mironov, C. Cerutti, K. Bentley, A. Philippides, F. Zanardi, M. Bacigaluppi, , M. Giannotta

This study identifies Gpr126 as a regulator of BBB development and shows its detrimental role in ischemic stroke, with potential therapeutic implications.

bioRxiv · Sep 9, 2022 · PreprintCell Biology

Brain de novo transcriptome assembly of a toad species showing polymorphic anti-predatory behavior

A. Chiocchio, P. Libro, G. Martino, R. Bisconti, T. Castrignano, D. Canestrelli

The paper assembles and annotates the first de novo brain transcriptome of Bombina pachypus, a toad species with polymorphic anti-predatory behavior, using RNA-Seq data from individuals with distinct behavioral phenotypes.

bioRxiv · Aug 3, 2022Evolutionary Biology

Shock or jump: deimatic behaviour is repeatable and polymorphic in a yellow-bellied toad

A. Chiocchio, G. Martino, R. Bisconti, C. Carere, D. Canestrelli

This study shows that deimatic displays in yellow-bellied toads vary between individuals and exhibit two distinct behavioural profiles.

bioRxiv · Apr 29, 2022 · PreprintEcology

Heparin protects human neural progenitor cells from Zika Virus-induced cell death and preserves their differentiation into mature neural-glia cells

I. Pagani, L. Ottoboni, P. Podini, S. Ghezzi, E. Brambilla, S. Bezukladova, D. Corti, M. E. Bianchi, M. R. Capobianchi, E. A. Yates, G. Martino, E. Vicenzi

bioRxiv · May 5, 2021 · PreprintMicrobiology

CCNE1 amplification is synthetic-lethal with PKMYT1 kinase inhibition

D. Gallo, J. T. F. Young, J. Fourtounis, G. Martino, A. Alvarez-Quilon, C. Bernier, N. M. Duffy, R. Papp, A. Roulston, R. Stocco, J. Szychowski, A. Veloso, H. Alam, P. S. Baruah, A. Bonneau Fortin, , D. Durocher

The paper identifies PKMYT1 as a therapeutic target for CCNE1-amplified cancers, showing that its inhibition leads to synthetic lethality and tumor regression in combination with gemcitabine.

bioRxiv · Apr 8, 2021Cancer Biology

CIP2A is a prime synthetic-lethal target for BRCA-mutated cancers

S. Adam, S. E. Rossi, N. Moatti, M. De Marco Zompit, T. F. Ng, A. Alvarez-Quilon, J. Desjardins, V. Bhaskaran, G. Martino, D. Setiaputra, S. M. Noordermeer, T. K. Ohsumi, N. Hustedt, R. K. Szilard, N. Chaudhary, , D. Durocher

The paper identifies CIP2A as a synthetic-lethal target in BRCA-mutated cancers by showing its essential role in mitotic chromosome stability and its interaction with TOPBP1.

bioRxiv · Feb 8, 2021 · PreprintCancer Biology

Drilling down hotspots of intraspecific diversity to bring them into on-ground conservation of threatened species

M. Zampiglia, R. Bisconti, L. Maiorano, G. Aloise, A. Siclari, F. Pellegrino, G. Martino, A. Pezzarossa, A. Chiocchio, C. Martino, G. Nascetti, D. Canestrelli

The paper assesses the spatial and temporal dynamics of genetic diversity in a threatened toad species, highlighting the need for finer-scale conservation strategies.

bioRxiv · Sep 18, 2018Evolutionary Biology