S. F. Marino

Structure-based humanization of a therapeutic antibody for Multiple Myeloma

The paper describes a method to humanize a therapeutic antibody for Multiple Myeloma using structural information to optimize binding affinity while minimizing antigenicity.

SARS-CoV-2 has not emerged in roe, red or fallow deer in Germany or Austria during the COVID 19 pandemic

The paper tests deer samples from Germany and Austria for SARS-CoV-2 exposure and finds no evidence of infection during the pandemic.

Disrupting the CD177:proteinase 3 membrane complex reduces anti-PR3 antibody-induced neutrophil activation

This study shows that disrupting the CD177:PR3 membrane complex reduces anti-PR3 antibody-induced neutrophil activation in ANCA-associated vasculitis.

Structure of a cytochrome-based bacterial nanowire

Cryo-electron microscopy reveals the structure of a c-type cytochrome filament forming a bacterial nanowire in Geobacter sulfurreducens.

Rapid and efficient C-terminal labeling of nanobodies for DNA-PAINT

The paper develops an optimized method for labeling nanobodies with DNA oligomers for DNA-PAINT, enabling efficient and straightforward superresolution imaging.