Sclerostin blockade inhibits bone resorption through PDGF receptor signaling in osteoblast lineage cells
C. Thouverey, P. Apostolides, J. Brun, J. Caverzasio, S. Ferrari
bioRxiv · Sep 11, 2023Pharmacology & Toxicology
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S. Ferrari
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2018-2023 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 13 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship6 papers
Recent·Most cited
Cell wall integrity modulates a PHYTOCHROME-INTERACTING FACTOR (PIF) - HOOKLESS1 (HLS1) signalling module controlling apical hook formation in Arabidopsis.
R. Lorrai, O. Erguvan, S. Raggi, K. Jonsson, J. Siroka, D. Tarkowska, O. Novak, S. Verger, S. Robert, S. Ferrari
This study shows that cell wall integrity modulates apical hook formation in Arabidopsis by affecting the PIF4/5-HLS1 signalling module and gibberellin levels.
bioRxiv · Aug 5, 2023 · PreprintPlant Biology
Adipose-tissue derived signals control bone remodelling.
M.-B. Madel, H. Fu, D. Pierroz, M. Schiffrin, C. Winkler, A. Wilson, C. Pochon, B. Toffoli, J.-Y. Jouzeau, F. Gilardi, S. Ferrari, N. Bonnet, C. BLIN-WAKKACH, B. Desvergne, D. MOULIN
This study shows that adipose-derived signals, particularly adiponectin, regulate bone remodeling by inhibiting osteoclastogenesis and that AdipoRon can treat inflammatory bone loss.
bioRxiv · Mar 2, 2020 · PreprintCell Biology
Geometry alone influences stem cell differentiation in a precision 3D printed stem cell niche
E. Prina, L. Sidney, M. Tromayer, J. Moore, R. Liska, M. Bertolin, S. Ferrari, A. Hopkinson, H. Dua, J. Yang, R. Wildman, F. R. Rose
The paper shows that precise 3D printed geometric structures influence stem cell differentiation without exogenous signaling molecules.
bioRxiv · Dec 9, 2018Bioengineering
Pharmacophore-guided discovery of CDC25 inhibitors causing cell cycle arrest and cell death
Z. Kabakci, S. Kaeppeli, G. Cozza, C. Cantu, C. Koenig, J. Toggweiler, C. Gentili, G. Ribaudo, G. Zagotto, K. Basler, L. A. Pinna, S. Ferrari
This study identifies CDC25 inhibitors that induce cell cycle arrest and cell death through a mixed-type mechanism, validated in 2D cultures and 3D organoids.
bioRxiv · Apr 27, 2018Cancer Biology