Author

J. Brun

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 2 Bioengineering· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

M. Hensen· 2 shared N. Zitzmann· 2 shared S. Vasiljevic· 2 shared W. B. Struwe· 2 shared A. Marcellan· 1 shared A. Olerinyova· 1 shared A. V. Chandran· 1 shared B. Gangadharan· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiophysics

M. Hensen

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Cooperativity and induced oligomerisation control the interaction of SARS- CoV-2 with its cellular receptor and patient-derived antibodies

R. Asor, A. Olerinyova, S. A. Burnap, M. S. Kushwah, F. Soltermann, L. P. Rudden, M. Hensen, S. Vasiljevic, J. Brun, M. Hill, L. Chang, W. Dejnirattisai, P. Supasa, J. Mongkolsapaya, D. Zhou, , P. Kukura

The paper investigates how multivalent interactions between SARS-CoV-2 spike protein, ACE2 receptor, and patient-derived antibodies influence viral entry and antibody inhibition.

bioRxiv · Sep 14, 2023 · PreprintBiophysics

Sclerostin blockade inhibits bone resorption through PDGF receptor signaling in osteoblast lineage cells

C. Thouverey, P. Apostolides, J. Brun, J. Caverzasio, S. Ferrari

bioRxiv · Sep 11, 2023Pharmacology & Toxicology

Anisotropic dense collagen hydrogels possessing two ranges of porosity to create the adequate microenvironment for muscle bundles: a step towards skeletal muscle modeling

M. Camman, P. Joanne, J. Brun, A. Marcellan, J. Dumont, O. Agbulut, C. Helary

This paper develops anisotropic dense collagen hydrogels with two porosity ranges to support myoblast differentiation into myotubes and mimic skeletal muscle ECM properties.

bioRxiv · Jun 19, 2022 · PreprintBioengineering

Human basigin (CD147) does not directly interact with SARS-CoV-2 spike glycoprotein

R. J. Ragotte, D. Pulido, F. R. Donnellan, G. Gorini, H. Davies, J. Brun, L. D. King, K. Skinner, S. J. Draper

This study shows that SARS-CoV-2 spike glycoprotein does not directly interact with human basigin (CD147), challenging its role as a co-receptor for viral entry.

bioRxiv · Feb 22, 2021Biochemistry

Analysis of SARS-CoV-2 spike glycosylation reveals shedding of a vaccine candidate

J. Brun, S. Vasiljevic, B. Gangadharan, M. Hensen, A. V. Chandran, M. L. Hill, J. L. Kiappes, R. A. Dwek, D. S. Alonzi, W. B. Struwe, N. Zitzmann

The paper compares glycosylation patterns between SARS-CoV-2 viral spikes and a vaccine candidate, showing differences in secretion pathways and potential implications for immune response and vaccine design.

bioRxiv · Nov 16, 2020 · PreprintBiochemistry

Lipid composition but not curvature is a determinant of a low molecular mobility within HIV-1 lipid envelope

I. Urbancic, J. Brun, D. Shrestha, D. Waithe, C. Eggeling, J. Chojnacki

The paper investigates the factors affecting molecular mobility on HIV-1 lipid envelopes using STED-FCS, finding that lipid composition and rigidity, not curvature, determine low mobility.

bioRxiv · May 4, 2018Biophysics