Overcoming donor variability and risks associated with fecal microbiota transplants through bacteriophage-mediated treatments
T. S. Rasmussen, X. Mao, S. Forster, S. B. Larsen, A. von Munchow, K. D. Tranaes, A. Brunse, F. Larsen, J. L. Castro-Mejia, S. Adamberg, A. K. Hansen, K. Adamberg, C. H. F. Hansen, D. S. Nielsen
This study develops modified fecal virome transplants (FVT) to reduce donor variability and infection risks in treating C. difficile infections, showing improved efficacy and safety in a mouse model.
bioRxiv · Mar 17, 2023Microbiology