Author

S. H. Khan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 3 Approach:experimental assay· 2 Assay:protein structure· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:clinical cohort / trial· 1

Frequent Co-Authors

C. D. Okafor· 2 shared A. I. khan· 1 shared A. S. G. Faruque· 1 shared B. Taneja· 1 shared C. Latka· 1 shared D. Hercules· 1 shared E. A. Ortlund· 1 shared E. Elacqua· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersBiochemistry

C. D. Okafor

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Author profile →

4 papers

Recent·Most cited

Ligand-induced shifts in conformational ensembles that predict transcriptional activation

S. H. Khan, S. M. Braet, S. J. Koehler, E. Elacqua, G. S. Anand, C. D. Okafor

The paper uses molecular dynamics simulations and experimental validation to show that conformational ensembles of nuclear receptors predict ligand-induced transcriptional responses.

bioRxiv · May 29, 2022 · PreprintBiochemistry

Evolutionary tuning of a key helix drove androgen selectivity

C. D. Okafor, J. K. Colucci, M. L. Cato, S. H. Khan, K. Cottrill, D. Hercules, G. Eick, J. W. Thornton, E. A. Ortlund

The paper investigates how evolutionary changes in helix 10 of androgen receptors drove ligand selectivity by analyzing ancestral proteins and biophysical mechanisms.

bioRxiv · Jul 21, 2021 · PreprintEvolutionary Biology

Structural analysis of Sub16 sedolisin of Trichophyton rubrum reveals a flexible nature of its pro domain

C. Latka, J. Bikshapathi, P. Aggarwal, N. S. Bhavesh, R. Chakraborty, S. H. Khan, B. Taneja

The paper investigates the structural flexibility of the pro domain of Sub16, a sedolisin from T. rubrum, showing it is stabilized when complexed with the catalytic domain.

bioRxiv · Jan 28, 2020 · PreprintBiophysics

Different features of cholera in malnourished and non-malnourised children: analysis of 10-year surveillance data from a large diarrheal disease hospital in urban Bangladesh

S. Nuzhat, M. I. Hossain, N. J. Shaly, R. Islam, S. H. Khan, P. K. Bardhan, A. I. khan, A. S. G. Faruque, M. J. Chisti, T. Ahmed

This study compares clinical features of cholera in malnourished and non-malnourished children using surveillance data from Bangladesh, finding differences in presentation and hospitalization.

bioRxiv · Nov 2, 2018Microbiology