Author

S. H. Mohamed

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:fungi (other)· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

E. R. Ballou· 2 shared G. Vande Velde· 2 shared M. S. Fu· 2 shared R. A. Drummond· 2 shared A. Alselami· 1 shared A. Chapuis· 1 shared C. Ding· 1 shared D. M. MacCallum· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

E. R. Ballou

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

CSF1R inhibition by PLX5622 reduces pulmonary fungal infection by depleting MHCIIhi interstitial lung macrophages

S. H. Mohamed, E. Vonhoffelen, M. S. Fu, E. Cosway, G. Anderson, G. Vande Velde, R. A. Drummond

PLX5622 reduces pulmonary fungal infection by depleting MHCIIhi interstitial lung macrophages, which are key infection reservoirs for Cryptococcus neoformans.

bioRxiv · Nov 18, 2022 · PreprintImmunology

Microglia protect fungi against copper starvation and promote brain infection

S. H. Mohamed, M. S. Fu, S. Hain, A. Alselami, E. Vanhoffelen, Y. Li, E. Bojang, R. Lukande, E. R. Ballou, R. C. May, C. Ding, G. Vande Velde, R. A. Drummond

This study shows microglia support cryptococcal brain infections by hosting fungal growth and facilitating copper acquisition, and demonstrates that IFNγ can block this process.

bioRxiv · Sep 7, 2022 · PreprintImmunology

Host environmental conditions induce small fungal cell size and alter population heterogeneity in Cryptococcus neoformans

X. Zhou, H. Zafar, P. C. S. Sephton-Clark, S. H. Mohamed, A. Chapuis, M. Makarova, D. M. MacCallum, R. Drummond, I. M. Dambuza, E. R. Ballou

The paper investigates the relationship between titan cells, small cells, and titanides in Cryptococcus neoformans, showing their shared features and impact on aneuploidy and drug resistance.

bioRxiv · Jan 3, 2020 · PreprintMicrobiology