Author

S. Hain

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

A. Alselami· 1 shared A. R. Clark· 1 shared C. Ding· 1 shared C. Lockwood· 1 shared D. A. Tennant· 1 shared D. Abdelmottaleb· 1 shared E. Bojang· 1 shared E. R. Ballou· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. Alselami

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Author profile →

2 papers

Recent·Most cited

The glucocorticoid dexamethasone inhibits HIF-1alpha stabilisation and metabolic reprogramming in lipopolysaccharide-stimulated primary macrophages.

S. A. Clayton, C. Lockwood, J. D. O'Neil, K. K. Daley, S. Hain, D. Abdelmottaleb, O. O. Bolimowska, D. A. Tennant, A. R. Clark

This study shows dexamethasone inhibits HIF-1α stabilization and reduces GLUT1 expression in lipopolysaccharide-stimulated macrophages, impairing glucose uptake and metabolic reprogramming.

bioRxiv · Sep 20, 2023Immunology

Microglia protect fungi against copper starvation and promote brain infection

S. H. Mohamed, M. S. Fu, S. Hain, A. Alselami, E. Vanhoffelen, Y. Li, E. Bojang, R. Lukande, E. R. Ballou, R. C. May, C. Ding, G. Vande Velde, R. A. Drummond

This study shows microglia support cryptococcal brain infections by hosting fungal growth and facilitating copper acquisition, and demonstrates that IFNγ can block this process.

bioRxiv · Sep 7, 2022 · PreprintImmunology