CSF1R inhibition by PLX5622 reduces pulmonary fungal infection by depleting MHCIIhi interstitial lung macrophages
S. H. Mohamed, E. Vonhoffelen, M. S. Fu, E. Cosway, G. Anderson, G. Vande Velde, R. A. Drummond
PLX5622 reduces pulmonary fungal infection by depleting MHCIIhi interstitial lung macrophages, which are key infection reservoirs for Cryptococcus neoformans.
bioRxiv · Nov 18, 2022 · PreprintImmunology