Author

S. H. Saber

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

G. Balistreri· 2 shared L. Kareinen· 2 shared M. Joensuu· 2 shared O. Vapalahti· 2 shared R. Kant· 2 shared R. Ojha· 2 shared T. Sironen· 2 shared T. Strandin· 2 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersMicrobiology

G. Balistreri

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Complete Protection from SARS-CoV-2 Lung Infection in Mice Through Combined Intranasal Delivery of PIKfyve Kinase and TMPRSS2 Protease Inhibitors

R. Kant, L. Kareinen, R. Ojha, T. Strandin, S. H. Saber, A. Lesnikova, S. Kuivanen, T. Sironen, M. Joensuu, O. Vapalahti, T. Kirchhausen, A. Kipar, G. Balistreri

This study shows that combining PIKfyve and TMPRSS2 inhibitors intranasally protects mice from SARS-CoV-2 lung infection and reduces cell death.

bioRxiv · Jul 19, 2023 · PreprintMicrobiology

Inhibition of host N-myristoylation compromises the infectivity of SARS-CoV-2 due to Golgi-bypassing egress from lysosomes and endoplasmic reticulum

S. H. Saber, M. R. Shaker, J. Sng, N. Yak, S. D. Morrison, S. Pars, H. Zheng, G. Pietrogrande, T. Binder, S. Lu, M. Floetenmeyer, R. Ojha, T. Quirin, J. Ruuska, T. Smura, , M. Joensuu

This study shows that inhibiting host N-myristoylation reduces SARS-CoV-2 infectivity by impairing viral envelope protein maturation and causing Golgi-bypassing egress.

bioRxiv · Mar 3, 2023 · PreprintMicrobiology