Author

S. Herrera-Alvarez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:fungi (other)· 1 Organism:mouse· 1 Organism:multiple species· 1

Frequent Co-Authors

A. J. Crawford· 3 shared K. Zhang· 2 shared L. Yang· 2 shared M. d. P. Rodriguez-Ordonez· 2 shared P. Andolfatto· 2 shared S. Dobler· 2 shared S. Mohammadi· 2 shared A. Harpak· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersEvolutionary Biology

A. J. Crawford

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3 papers

Recent·Most cited

Constraints on the evolution of toxin-resistant Na,K-ATPases have limited dependence on sequence divergence

S. Mohammadi, S. Herrera-Alvarez, L. Yang, M. d. P. Rodriguez-Ordonez, K. Zhang, J. Storz, S. Dobler, A. J. Crawford, P. Andolfatto

The paper investigates how intramolecular epistasis affects the evolution of CTS-resistant Na,K-ATPases, finding that resistance substitutions have pleiotropic effects independent of sequence divergence.

bioRxiv · Nov 29, 2021Evolutionary Biology

Concerted evolution reveals co-adapted amino acid substitutions in Na+K+-ATPase of frogs that prey on toxic toads

S. Mohammadi, L. Yang, A. Harpak, S. Herrera-Alvarez, M. d. P. Rodriguez-Ordonez, J. Peng, K. Zhang, J. F. Storz, S. Dobler, A. J. Crawford, P. Andolfatto

The paper shows that selection maintains adaptive division-of-labor between tandem duplicates of ATP1A1 in frogs, countering gene conversion to confer toxin resistance.

bioRxiv · Aug 4, 2020Evolutionary Biology

How to make a rodent giant: Genomic basis and tradeoffs of gigantism in the capybara, the world’s largest rodent

S. Herrera-Alvarez, E. Karlsson, O. A. Ryder, K. Lindblad-Toh, A. J. Crawford

This study sequenced the capybara genome to investigate the genetic basis of gigantism and related tradeoffs, finding elevated mutation load and novel anticancer mechanisms.

bioRxiv · Sep 23, 2018Evolutionary Biology