Crippling the bacterial cell wall molecular machinery
A. H. Williams, I. Boneca, R. Wheeler, A.-E. Deghmane, I. Santecchia, F. Impens, P. A. D. Bastos, S. Hicham, M. Moya Nilges, C. Malosse, J. Chamot-Rooke, A. Haouz, W. P. Robins, M.-K. Taha
This study identifies the role of lytic transglycosylase LtgA in bacterial cell wall integrity and shows that targeting it can impair Neisseria meningitidis fitness during infection.
bioRxiv · Apr 12, 2019 · PreprintBiochemistry