Author

W. P. Robins

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

J. J. Mekalanos· 3 shared A. C. Kruse· 1 shared A. H. Williams· 1 shared A. Haouz· 1 shared A.-E. Deghmane· 1 shared B. T. Meader· 1 shared C. Malosse· 1 shared D. S. Marks· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersMicrobiology

J. J. Mekalanos

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cell density-dependent death triggered by viral palindromic DNA sequences

W. P. Robins, B. T. Meader, J. Toska, J. J. Mekalanos

The paper identifies palindromic DNA sequences that trigger cell-density dependent death in Vibrio cholerae via the DdmABC/PriA system during DNA replication stress.

bioRxiv · Nov 18, 2022 · PreprintMicrobiology

Covariance predicts conserved protein residue interactions important to the emergence and continued evolution of SARS-CoV-2 as a human pathogen

W. P. Robins, J. J. Mekalanos

The paper identifies conserved protein residue interactions in SARS-CoV-2 related coronaviruses that correlate with their emergence and evolution as human pathogens.

bioRxiv · Jan 13, 2022Microbiology

Crippling the bacterial cell wall molecular machinery

A. H. Williams, I. Boneca, R. Wheeler, A.-E. Deghmane, I. Santecchia, F. Impens, P. A. D. Bastos, S. Hicham, M. Moya Nilges, C. Malosse, J. Chamot-Rooke, A. Haouz, W. P. Robins, M.-K. Taha

This study identifies the role of lytic transglycosylase LtgA in bacterial cell wall integrity and shows that targeting it can impair Neisseria meningitidis fitness during infection.

bioRxiv · Apr 12, 2019 · PreprintBiochemistry

Structure and mutagenic analysis of the lipid II flippase MurJ from Escherichia coli

S. Zheng, L.-T. Sham, F. A. Rubino, K. Brock, W. P. Robins, J. J. Mekalanos, D. S. Marks, T. G. Bernhardt, A. C. Kruse

The paper reports the crystal structure of MurJ from E. coli, performs mutagenesis to map functional sites, and identifies co-evolved interactions supporting a rocker-switch model for lipid II transport.

bioRxiv · Feb 19, 2018Biochemistry