Author

S. Houghton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. Redmond· 2 shared A. Murison· 1 shared A. Trivedi· 1 shared B. E. Nilsson-Payant· 1 shared B. Hadland· 1 shared B. R. tenOever· 1 shared B. Summers· 1 shared C. Badwe· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

D. Redmond

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Lymphatic Dysfunction Models an Autoimmune Emphysema Phenotype of Chronic Obstructive Pulmonary Disease

B. Summers, K. Kim, T. M. Lu, S. Houghton, J. R. Quintero, J. Cala-Garcia, T. Pannellini, F. Polverino, R. Lis, A. Trivedi, H. O. Reed

This study shows that lymphatic dysfunction drives lung injury and autoimmune emphysema in COPD by promoting TLO formation and autoantibody production in mice, with similar patterns observed in human COPD patients.

bioRxiv · Oct 31, 2023 · PreprintPathology

Transcriptional Activation of Regenerative Hematopoiesis via Vascular Niche Sensing

T. Itkin, S. Houghton, R. Schreiner, Y. Lin, C. Badwe, V. Voisin, A. Murison, N. Seyedhassantehrani, K. B. Kaufmann, L. Garcia-Prat, G. T. Booth, F. Geng, Y. Liu, J. M. Gomez-Salinero, J.-H. Shieh, , S. Rafii

The paper identifies Fli-1's role in regulating HSC activation during regenerative hematopoiesis by enabling niche signaling and functional recovery.

bioRxiv · Mar 27, 2023 · PreprintCell Biology

Identification of Candidate COVID-19 Therapeutics using hPSC-derived Lung Organoids

Y. Han, L. Yang, X. Duan, F. Duan, B. E. Nilsson-Payant, T. M. Yaron, P. Wang, X. Tang, T. Zhang, Z. Zhao, Y. Bram, D. Redmond, S. Houghton, D. Nguyen, D. Xu, , S. Chen

This study uses hPSC-derived lung organoids to identify FDA-approved drugs that inhibit SARS-CoV-2 entry and reduce infection in a model of human COVID-19.

bioRxiv · May 5, 2020 · PreprintMicrobiology