The yeast Gcn2 protein kinase mediates P-body formation both through its activity with eIF2α and with non-canonical substrates
V. Stonys, S. Hubbard, M. P. Ashe, Chris Grant
This study shows that yeast Gcn2 promotes P-body formation through eIF2α phosphorylation and Smu2-dependent mRNA granule maturation, even when eIF2α phosphorylation is blocked.
bioRxiv · Nov 9, 2026 · PreprintCell Biology