Author

S. Hultmark

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

J. Larsson· 2 shared A. Backstrom· 1 shared A. Baudet· 1 shared A. Subramaniam· 1 shared C. Sanden· 1 shared D. Bryder· 1 shared E. Arvidsson· 1 shared G. Juliusson· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

J. Larsson

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2 papers

Recent·Most cited

Inducing synthetic lethality for selective targeting of acute myeloid leukemia cells harboring STAG2 mutations

A. Subramaniam, C. Sanden, L. Moura-Castro, K. Zemaitis, L. Schmiderer, A. Backstrom, E. Arvidsson, S. Hultmark, N. Miharada, K. Paulsson, T. Fioretos, J. Larsson

This study demonstrates that partial STAG1 perturbation selectively kills STAG2-mutated AML cells while sparing normal HSCs, showing synthetic lethality in xenograft models.

bioRxiv · Feb 18, 2022Cancer Biology

Hepatic Leukemia Factor supports the propagation of leukemia and hematopoietic stem cell function during stress-induced regeneration.

A. Baudet, K. Komorowska, S. Hultmark, M. Chapellier, K. Miharada, J. Larsson, D. Bryder, M. Jaras, G. Juliusson, M. Magnusson

This study shows HLF is essential for stress-induced hematopoietic regeneration and leukemia propagation in aged HSCs but not for normal aging hematopoiesis.

bioRxiv · Mar 5, 2021 · PreprintCancer Biology