Author

N. Miharada

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

A. Backstrom· 1 shared A. Subramaniam· 1 shared C. Sanden· 1 shared D. Song· 1 shared E. Arvidsson· 1 shared G. Takahashi· 1 shared J. Larsson· 1 shared J. Li· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. Backstrom

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Retinoids rescue ceruloplasmin secretion and alleviate oxidative stress in Wilson's disease-specific hepatocytes

D. Song, G. Takahashi, Y.-W. Zheng, M. Matsuo-Takasaki, J. Li, M. Takami, Y. An, Y. Hemmi, N. Miharada, T. Fujioka, M. Noguchi, T. Nakajima, m. K. Saito, Y. Nakamura, T. Oda, , Y. Hayashi

This study uses patient-derived iPSCs to identify retinoids as potential therapeutics for Wilson's disease by rescuing ceruloplasmin secretion and reducing oxidative stress.

Human Molecular Genetics · Oct 28, 2022Peer-reviewedCell Biology

Inducing synthetic lethality for selective targeting of acute myeloid leukemia cells harboring STAG2 mutations

A. Subramaniam, C. Sanden, L. Moura-Castro, K. Zemaitis, L. Schmiderer, A. Backstrom, E. Arvidsson, S. Hultmark, N. Miharada, K. Paulsson, T. Fioretos, J. Larsson

This study demonstrates that partial STAG1 perturbation selectively kills STAG2-mutated AML cells while sparing normal HSCs, showing synthetic lethality in xenograft models.

bioRxiv · Feb 18, 2022Cancer Biology