Author

S. J. Benkovic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1

Frequent Co-Authors

A. B. Pinkerton· 1 shared A. Steffy· 1 shared B. Sengupta· 1 shared C. A. Hassig· 1 shared C. Curtis· 1 shared E. J. Curtis· 1 shared E. Tse· 1 shared G. K. Marinov· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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1 shared paperCancer Biology

A. B. Pinkerton

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Rampant transcription replication conflict creates therapeutic vulnerability in extrachromosomal DNA containing cancers

J. Tang, N. E. Weiser, G. Wang, S. Chowdhry, E. J. Curtis, Y. Zhao, I. T.-L. Wong, G. K. Marinov, R. Li, P. Hanoian, E. Tse, R. Hansen, J. Plum, A. Steffy, S. Milutinovic, , H. Y. Chang

This paper identifies transcription-replication conflict as a vulnerability in ecDNA-containing cancers and demonstrates that CHK1 inhibition selectively kills these tumors.

bioRxiv · Mar 29, 2024 · PreprintCancer Biology

Structural basis of the T4 bacteriophage primosome assembly and primer synthesis

X. Feng, M. M. Spiering, R. d. L. A. Santos, S. J. Benkovic, H. Li

This study reports cryo-EM structures of T4 bacteriophage primosome assembly intermediates, revealing how the helicase and primase interact and synthesize RNA primers.

bioRxiv · May 3, 2023Biochemistry

PCNA monoubiquitination is regulated by diffusion of Rad6/Rad18 complexes along RPA filaments

M. Li, B. Sengupta, S. J. Benkovic, T. H. Lee, M. Hedglin

The paper investigates how Rad6/Rad18 complexes move along RPA filaments to regulate PCNA monoubiquitination during translesion DNA synthesis.

bioRxiv · Aug 11, 2020Biochemistry