Author

A. B. Pinkerton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Assay:proteomics· 2 Assay:cryo-EM· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

C. A. Hassig· 2 shared A. Steffy· 1 shared B. E. Krumm· 1 shared B. L. Roth· 1 shared C. Curtis· 1 shared C.-T. Ma· 1 shared E. J. Curtis· 1 shared E. Sergienko· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

C. A. Hassig

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Author profile →

3 papers

Recent·Most cited

Rampant transcription replication conflict creates therapeutic vulnerability in extrachromosomal DNA containing cancers

J. Tang, N. E. Weiser, G. Wang, S. Chowdhry, E. J. Curtis, Y. Zhao, I. T.-L. Wong, G. K. Marinov, R. Li, P. Hanoian, E. Tse, R. Hansen, J. Plum, A. Steffy, S. Milutinovic, , H. Y. Chang

This paper identifies transcription-replication conflict as a vulnerability in ecDNA-containing cancers and demonstrates that CHK1 inhibition selectively kills these tumors.

bioRxiv · Mar 29, 2024 · PreprintCancer Biology

Neurotensin receptor allosterism revealed in complex with a biased allosteric modulator

B. E. Krumm, J. F. DiBerto, R. H. J. Olsen, H. J. Kang, S. T. Slocum, S. Zhang, R. T. Strachan, L. M. Slosky, A. B. Pinkerton, L. S. Barak, M. G. Caron, T. Kenakin, B. L. Roth

This study reveals the cryoEM structures of NTSR1 with and without SBI-553, showing its biased allosteric modulation of G protein and β-Arrestin signaling.

bioRxiv · Dec 26, 2022 · PreprintBiophysics

The serine-threonine kinase TAO3 promotes cancer invasion and tumor growth by facilitating trafficking of endosomes containing the invadopodia scaffold TKS5α

S. Iizuka, M. Quintavalle, J. Ceja Navarro, K. P. Gribbin, R. J. Ardecky, M. Abelman, C.-T. Ma, E. Sergienko, F.-Y. Zeng, I. Pass, G. Thomas, S. McWeeney, C. A. Hassig, A. B. Pinkerton, S. A. Courtneidge

bioRxiv · Feb 27, 2020Cancer Biology