Author

S. J. DePalma

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. S. Helms· 2 shared B. M. Baker· 2 shared C. D. Davidson· 2 shared A. Capilnasiu· 1 shared A. Chowdhury· 1 shared A. E. Stis· 1 shared A. P. Liu· 1 shared B. Baker· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersBioengineering

A. S. Helms

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Author profile →

3 papers

Recent·Most cited

Matrix architecture and mechanics regulate myofibril organization, costamere assembly, and contractility of engineered myocardial microtissues

S. J. DePalma, J. Jillberto, A. E. Stis, D. D. Huang, J. Lo, C. D. Davidson, A. Chowdhury, M. E. Jewett, H. Kobeissi, C. S. Chen, E. Lejeune, A. S. Helms, D. A. Nordsletten, B. Baker

This study investigates how matrix stiffness and alignment affect the structure and contractility of engineered myocardial tissues made from iPSC-derived cardiomyocytes.

bioRxiv · Oct 20, 2023Bioengineering

Mechanical intercellular communication via matrix-borne cell force transmission during vascular network formation

C. D. Davidson, S. J. DePalma, W. Y. Wang, J. L. Kamen, D. K. P. Jayco, B. M. Baker

This study investigates mechanical intercellular communication during vascular network formation using synthetic matrices and identifies calcium signaling's role in cell migration and network assembly.

bioRxiv · Aug 17, 2021Bioengineering

Biomechanics and Myofibrillar Alignment Enhance Contractile Development and Reproducibility in Stem Cell Derived Cardiac Muscle

Y.-C. Tsan, Y.-T. Zhao, S. J. DePalma, A. Capilnasiu, Y.-W. Wu, B. Elder, I. Panse, S. Friedline, T. S. O'Leary, N. Wubshet, K. K. Y. Ho, M. J. Previs, D. Nordsletten, B. M. Baker, L. L. Isom, , A. S. Helms

This study develops a 2D platform to enhance contractile development and reproducibility in stem cell-derived cardiac muscle by controlling biomechanics and myofibrillar alignment.

bioRxiv · May 23, 2021 · PreprintCell Biology