Author

S. J. Hatsell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. N. Economides· 2 shared S. Aykul· 2 shared S. Brydges· 2 shared V. Idone· 2 shared A. J. Murphy· 1 shared E. J. Goebel· 1 shared J. B. Lees-Shepard· 1 shared J. Lees-Shepard· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

A. N. Economides

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Coordinate regulation of Activin and Bone Morphogenetic Protein signaling by a lysosomal trafficking switch

W. W. Hom, S. Aykul, L. Panagis, K. Patel, S. Brydges, E. J. Goebel, K. N. Lydon, J. B. Lees-Shepard, S. J. Hatsell, V. Idone, A. N. Economides

The paper shows that ActA forms non-signaling complexes with ACVR1 that are trafficked to lysosomes and degraded, unlike Activin B, AC, and AB which remain on the surface.

bioRxiv · Jan 29, 2024 · PreprintCell Biology

ACVR1 antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressiva (FOP) by activating FOP-mutant ACVR1

S. Aykul, L. Huang, L. Wang, N. Das, S. Reisman, Y. Ray, Q. Zhang, N. Rothman, K. C. Nannuru, V. Kamat, S. Brydges, L. Troncone, L. Johnsen, P. B. Yu, S. Fazio, , S. J. Hatsell

This study shows that ACVR1 antibodies, intended to block ACVR1 activation, instead stimulate heterotopic ossification in FOP by activating FOP-mutant ACVR1 through dimerization.

bioRxiv · Jul 18, 2021Biochemistry