Author

S. J. Neil

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 4 Research Focus:cell signaling & trafficking· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:metagenomics· 1

Frequent Co-Authors

H. Wilson· 3 shared H. Winstone· 3 shared M. J. Lista· 3 shared C. M. Swanson· 2 shared C. Odendall· 2 shared D. Kmiec· 2 shared I. A. Taylor· 2 shared J. Wanford· 2 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

H. Wilson

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Differential dysregulation of β-TrCP1 and -2 by HIV-1 Vpu leads to inhibition of canonical and non-canonical NF-κB pathways in infected cells

S. Pickering, J. Sumner, C. Kerridge, S. J. Neil

This study shows HIV-1 Vpu inhibits both canonical and non-canonical NF-κB pathways by differentially targeting β-TrCP1 and β-TrCP2, affecting immune responses and antiviral defenses in infected cells.

bioRxiv · Nov 30, 2022 · PreprintMicrobiology

The P681H mutation in the Spike glycoprotein escapes IFITM restriction and is necessary for type I interferon resistance in the SARS-CoV-2 alpha variant

M. J. Lista, H. Winstone, H. Wilson, A. Dyer, S. Pickering, R. P. Galao, G. De Lorenzo, V. Cowton, W. Furnon, N. M. Suarez, R. Orton, M. Palmirini, A. H. Patel, L. B. Snell, G. Nebbia, , S. J. Neil

This paper shows the P681H mutation in the SARS-CoV-2 alpha variant's Spike protein enables resistance to type I interferon and IFITM proteins, enhancing viral entry and transmission.

bioRxiv · Aug 11, 2022Microbiology

A nuclear export signal in KHNYN required for its antiviral activity evolved as ZAP emerged in tetrapods

M. J. Lista, M. Ficarelli, H. Wilson, D. Kmiec, R. Youle, J. Wanford, H. Winstone, C. Odendall, I. A. Taylor, S. J. Neil, C. M. Swanson

bioRxiv · May 31, 2022Microbiology

Regulation of KHNYN antiviral activity by the extended di-KH domain and nucleo-cytoplasmic trafficking

M. J. Lista, R. P. Galao, M. Ficarelli, D. Kmiec, H. Wilson, H. Winstone, E. R. Morris, H. E. Mischo, J. Wanford, R. Youle, C. Odendall, I. A. Taylor, S. J. Neil, C. Swanson

This paper identifies the extended di-KH and CUBAN domains in KHNYN as critical for its antiviral activity and interaction with ZAP, showing that the CUBAN domain regulates trafficking and abundance.

bioRxiv · Dec 22, 2021 · PreprintMicrobiology