Author

V. Cowton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

G. De Lorenzo· 3 shared W. Furnon· 3 shared A. Dyer· 2 shared A. H. Patel· 2 shared C. M. Swanson· 2 shared G. Nebbia· 2 shared H. Wilson· 2 shared H. Winstone· 2 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

G. De Lorenzo

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Phenotyping the virulence of SARS-CoV-2 variants in hamsters by digital pathology and machine learning

G. R. Meehan, V. Herder, J. Allan, X. Huang, K. Kerr, D. C. Mendonca, G. Ilia, D. Wright, K. Nomikou, Q. Gu, S. M. Arias, G. De Lorenzo, V. Cowton, N. Upfold, N. Palmalux, , M. Palmarini

This study develops quantitative pipelines using digital pathology and machine learning to assess the virulence of SARS-CoV-2 variants in hamsters, showing that some Omicron sub-lineages have regained virulence.

bioRxiv · Aug 1, 2023Microbiology

The P681H mutation in the Spike glycoprotein escapes IFITM restriction and is necessary for type I interferon resistance in the SARS-CoV-2 alpha variant

M. J. Lista, H. Winstone, H. Wilson, A. Dyer, S. Pickering, R. P. Galao, G. De Lorenzo, V. Cowton, W. Furnon, N. M. Suarez, R. Orton, M. Palmirini, A. H. Patel, L. B. Snell, G. Nebbia, , S. J. Neil

This paper shows the P681H mutation in the SARS-CoV-2 alpha variant's Spike protein enables resistance to type I interferon and IFITM proteins, enhancing viral entry and transmission.

bioRxiv · Aug 11, 2022Microbiology

The P681H mutation in the Spike glycoprotein confers Type I interferon resistance in the SARS-CoV-2 alpha (B.1.1.7) variant

M. J. Lista, H. Winstone, H. Wilson, A. Dyer, S. Pickering, R. P. Galao, G. De Lorenzo, V. Cowton, W. Furnon, N. M. Suarez, R. Orton, M. Palmarini, A. H. Patel, L. B. Snell, G. Nebbia, , S. Neil

This study shows the P681H mutation in the SARS-CoV-2 alpha variant's Spike protein confers resistance to Type I interferon, enhancing viral replication by evading innate immune responses.

bioRxiv · Nov 9, 2021 · PreprintMicrobiology